Webinar: Acoustic assembly of biomaterials and engineered tissues (James Armstrong, Imperial College London)
In this talk, Dr. James Armstrong will discuss recent work that has demonstrated that ultrasound has been used to assemble musculoskeletal tissue, activate enzymes and trigger hydrogelation. First, he will outline how ultrasound standing waves can be used to remotely pattern cell populations, and how these ordered arrays can be immobilized in commonly used biomaterials and used to engineer aligned musculoskeletal tissues [1]. He will next describe how ultrasound fields can be used to controllably release calcium ions from liposomes in order to activate enzymatic catalysis and trigger hydrogelation [2]. He will then discuss how these novel processes can be used to provide enhanced strategies in tissue engineering, regenerative medicine and in vitro modelling.
[1] JPK Armstrong et al. Advanced Materials (2018).
[2] V Nele et al. Advanced Materials (2020).
Speaker
James received a PhD in Functional Nanomaterials from the University of Bristol in 2015. Later that year, he was awarded an Arthritis Research UK Foundation Fellowship to carry out research into how acoustic and magnetic fields could be used to remotely pattern cells and growth factors for osteochondral tissue engineering. He pursued this research at Imperial College London under the mentorship of Prof. Molly Stevens. He is now supported by an MRC/UKRI Innovation Rutherford Fund Fellowship and is leading research into new acoustic and material-based strategies for engineering advanced biological systems.
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